しょ

う

が

な

い

expression, adjective

1. there's no (other) way.
2. cannot be helped, unavoidable, inevitable, (there's) nothing one can do, having no choice, it is what it is.
3. it's no use (doing), pointless, useless, no good, insufficient, not enough. Oft. as 〜てもしょうがない.
4. hopeless (person), annoying, troublesome, awful.
5. cannot stand it, unbearable, cannot help (doing, feeling), dying (to do). As 〜てしょうがない or 〜でしょうがない.